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1658 Uppsatser om Platelet function - Sida 1 av 111

Evaluation of a standardized platelet concentration in samples from platelet concentrates measured over time with impedance aggregometry

Platelet transfusions can be necessary during treatment of patients with thrombocytopenia or impaired Platelet function. Platelet function in platelet concentrates (PC) deteriorate with storage time. Studying swirling is often used to control the quality of PC?s before transfusion but the method has some disadvantages. Therefore other methods can be useful, for example impedance aggregometry (IA, Multiplate® Analyzer) to measure Platelet function.     In this study the change in Platelet function over time was examined in buffy coat and apheresis platelets with IA where aggregation had been induced with adenosine diphosphate (ADP) and collagen.

QUALITY OF TACSI PLATELETS AND THEIR EFFECT ON THROMBOCYTOPENIA PATIENTS

 Conclusion:Medical treatment may have a role in platelet count after transfusion. Since the TACSI platelets passed the quality requirements, and the vast majority of patients platelet count increased after TACSI platelet transfusion, the TACSI platelets will replace the old method to produce platelets at the Uppsala University hospital.  Methods: A new approach that pools 8 buffy coats (TACSI platelets) that were separated into 2 units instead of 4-6 buffy coats pooled to 1 unit was investigated in this study. After the platelets were extracted from the buffy coats their quality was controlled and subsequently the platelet product was evaluated in 96 patients. Results: The results showed that 80 % of the platelet units passed the European quality requirements. Further, the platelet count was increased in most patients that received TACSI platelets. Conclusion: Medical treatment may have a role in platelet count after transfusion.

The impact of platelet storage time on transfusion results

Platelets are small fragments, but they are of crucial importance for the coagulation. The risk of spontaneous bleeding increases when the level of platelets falls below a thrombocyte particle concentration threshold value of 50 x 109/L. In those cases a platelet transfusion might be compulsory. Ongoing research tries to improve the quality of the platelets and to increase the safety of the method used. However, we still need to better understand which factors that affect how patients react upon platelet transfusion.

Trombocyträkning hos katt : en ny metod

Platelet aggregation is a major and common problem in blood samples from cats. This greatly affects the accuracy of counting of the platelets. Because of the difficulties in counting feline platelets, results for patients and reliable reference values for cat platelets are currently so inaccurate as to be almost useless in diagnosis of thrombocytopenia. In this study we used an effective method to prevent platelet aggregation. Blood was collected in CTAD test tubes and prostaglandin E1 was added to the blood sample.

Sample cradle prevents pre-analytic error on platelet counts but is not essential for hemoglobin measurement and prothrombin time

Introduction: It is recommended to place all the vacuum tubes directly on a sample cradle after vein puncture to prevent analytic error. This recommendation is not always easy to follow because the samples are taken by different professionals under different situations.  The three most common analyses, platelets count, haemoglobin and prothrombin time were tested.  Therefore, it was interesting to compare results from the three most common analyses with or without sample cradle, to evaluate the influence of this step on the result. Methods: Three analyses were preformed, using blood from 50 different persons. Each person gave two vacuum tubes, each contained 4.5mL of venous blood for the study.

Blödningsbenägenhet hos bengalkatter :

During the years 2005-2007 several cases of abnormal bleeding were seen after surgery in Bengal cats on veterinary clinics and animal hospitals in Sweden. In this study we have examined if the observed bleedings are due to an inherited defect of the coagulation cascade. Ten Bengal cats were tested for activated partial thromboplastin time (P-APT-time) and one-stage protrombin time (P-PK), and nine of these cats were tested for fibrinogen quantity (P-fibrinogen). Four of the tested cats had shown signs of an abnormal bleeding after surgery, and five of the cats were genetically related to these cats. One cat had a small bleeding wound at the internal base of the right auricle.

EN JÄMFÖRELSESTUDIE AV PLAST- OCH GLASHEMOCYTOMETRAR FÖR BERÄKNING AV BLODCELLER I VENÖST OCH KAPILLÄRT HELBLOD

Hematology-instruments that analyze blood cells can at specific cases be followed by manual counting with a hemocytometer. The plastic hemocytometer which has a fixed coverslip and is assigned for disposable use, appears to reduce the problems arising from the use of the traditional glass hemocytometer, for instance coverslip-application difficulty and dust particles. Capillary whole blood sampling may be useful for patients at the emergency department and in addition, a smaller volume of blood is taken compared to venous blood sampling. This study will focus on the platelet- and leukocyte count (PLT and WBC) in venous and capillary blood, in order to compare the plastic- and glass hemocytometers with Sysmex XN-2000 (Sysmex Corporation, Kobe, Japan), and verify if capillary whole blood sampling can be used for the measurement of these hematological parameters. 30 subjects donated both capillary- and venous blood samples and these blood samples were analyzed with glass- and plastic hemocytometers with Sysmex XN-2000 as the reference method.

Hur säkerställs effekten av marknadsföring när den outsourcas?

Outsourcing is today a common phenomenon among businesses in most industries. The term outsourcing means transferring the responsibility of performing a certain function to an external supplier. There are usually certain methods to investigate the effects and the outcome of a function that is performed by the company itself. When this function is performed by an external party, the complexity of the function will increase.This leads us to our purpose: Based on different theories clarify how a company ensures a desired effect out of marketing when this function is outsourced to a certain retail- and advertising agency.In this essay we have defined us to study one of Sweden´s leading mobile operators who have outsourced their sales management to a retail- and advertising agency. To get an additional point of view, we have included one of the mobile operator´s intermediates, which is a selling agent whose sales function is led by the retail- and advertising agency..

Världens ämne : Exkursioner i geografiundervisningen

This thesis is a case study of the search function on the University of Uppsala?s web site. The search function in this study was chosen since it exists on a large and complex web site and there were apparent lacks in the old version of the search function. The thesis highlights some of the problems that can appear in the development of a search function on a local site. One interesting find is that one of the most difficult issues is organizational and not technical.

Begreppet hållbar utveckling : Dess historia samt internationella och lokala användning

This thesis is a case study of the search function on the University of Uppsala?s web site. The search function in this study was chosen since it exists on a large and complex web site and there were apparent lacks in the old version of the search function. The thesis highlights some of the problems that can appear in the development of a search function on a local site. One interesting find is that one of the most difficult issues is organizational and not technical.

Ska vi träffas på biblioteket? En undersökning om folkbibliotekets funktion som mötesplats

The aim of this Master thesis is to study the public libraries' function as a place for people to meet. Four major questions are taken up: + Do the public libraries have the function of a meeting place? + How important do the librarians and the visitors find the libraries possible function as a meeting place? Do they think that this function is important? + What differs the public libraries from other places in society when it comes to the function of a meeting place? + What differences are there between a larger and a smaller library when it comes to the function of a meeting place ? The basis of this study are interviews with employees at a province library in Jönköping and at a smaller library in Sjöbo in Borås municipality. Our study deals with the history of public libraries, its functions as a meeting place, its architecture, culture, and statistics concerning numbers of visitors and loans of books. The conclusions that are drawn are that the public libraries have qualifications to function as a meeting place even if that isn't always the case.

Lokal sökfunktion : Fallstudie av utvecklandet av Uppsala Universitets sökfunktion

This thesis is a case study of the search function on the University of Uppsala?s web site. The search function in this study was chosen since it exists on a large and complex web site and there were apparent lacks in the old version of the search function. The thesis highlights some of the problems that can appear in the development of a search function on a local site. One interesting find is that one of the most difficult issues is organizational and not technical.

I ?Like? it. Jag ?Gillar? det : En studie av hur användares beteende och upplevelser påverkas av en "like-funktion", vid bildpublicering i sociala medier

The purpose of this paper has been to study how users experiences and behaviors are influenced by a "like" function, when publication of images in social media with the photo app Instagram as the selected base. In this study respondents has been part of a study regarding their experiences and behavior related to "like" function in Instagram. The results of the question form have then been analyzed to find patterns in their behavior and to exemplify/reinforce different type of user-behavior found in related scientific articles.The study has shown that the behavior of Instagram users is affected by the "like" function, when they believes that the function is a status marker that raises the interest for certain users by the number of likes. Through my results, I have been able to amplify and illustrate several theories of Goffman, Buckingham and Gripsrud which are presented in the report..

Optimal bredbandig vågform framtagen genom generaliserad osäkerhetsfunktion

The waveform of a radar signal affects the resolution in velocity and distance. The ambiguity function is used as an aid for analysing narrow band radar signals simultaneously in time and frequency. An analysing tool for wide band radar signals is missing.This thesis describes a generalised ambiguity function to be utilised for study of wide band signals. Waveforms are further synthesised with help of the developed analysing tool. The aim is to start with a certain ambiguity function and find a waveform that reproduces the same ambiguity function.Mathematical formulas are presented and implemented in Matlab to produce the wide band ambiguity function.

Det ligger nog i deras arbete att vara problemlösare : En kvalitativ fallstudie om HR-funktionens image och identitet ur ett intraorganisatoriskt perspektiv

Introduction: HR departments have been developed to take care of the organizations most important resource: the human being. HR as a function has however faced criticism claiming that the function does not entail any value to organizations. The rest of the organization often have a hard time understanding what HR?s daily work means and thereof not having a clear image of the function?s purpose or the function?s role in the organization Aim: The purpose of this study is to describe the relationship between the organization's view of the HR department (image) and the HR department's image of themselves (identity) in order to create a greater understanding of how the HR function successfully can be a well-functioning resource in an organization's overall business. Methodology: The study was conducted in the form of a case study. We have approached the issues by taking different perspective into account, which includes HR, managers and employees.

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